EP-1598: Modelisation of radiation response at various fractionation from histopathological prostate tumors
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چکیده
منابع مشابه
Response of human prostate cancer cells and tumors to combining PARP inhibition with ionizing radiation.
Radiation therapy remains a promising modality for curative treatment of localized prostate cancer, but dose-limiting toxicities significantly limit its effectiveness. Agents that enhance efficacy at lower radiation doses might have considerable value in increasing tumor control without compromising organ function. Here, we tested the hypothesis that the PARP inhibitor ABT-888 (veliparib) can e...
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C57BL/6XC3H F, mice were exposed postnatally to ionizing radiation for investigation of the role of postnatal age periods, fractionation schedule, and to a lesser degree the dose on carcinogenesis in various tissues. Starting on the 1st. 15th, or 42nd day of age, 4 experimental series were exposed to a total dose of 320 R, delivered in either single or fractionated exposures (4 or 7 days apart)...
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ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 2017
ISSN: 0167-8140
DOI: 10.1016/s0167-8140(17)32033-9